EFFECT OF CHRONOMODULATED ARTESUNATE ON RENAL AND HAEMATOLOGICAL TOXICITY IN CISPLATIN-TREATED WISTAR RATS

ABSTRACT     Cisplatin is a non-cell-cycle dependent chemotherapeutic agent used in the treatment of several common solid tumours. However, an array of serious toxicities…

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ANTIHYPERGLYCAEMIC AND ANTIBACTERIAL EVALUATION OF METHANOL TUBER EXTRACT OF CHLOROPHYTUM ALISMIFOLIUM BAKER (LILIACEAE)

ABSTRACT   Diabetes mellitus is a metabolic disorder which affects about 346 million people globally. Synthetic antidiabetic agents are expensive and also associated with side…

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ANXIOLYTIC PROPERTIES OF MITRACARPUS VILLOSUS (SW) DC.LEAF EXTRACTS IN MICE AND RATS

ABSTRACT   The leaf of Mitracarpusvillosus (Sw.) DC. (Rubiaceae) is used in West African folk medicine for the management of a plethora of stress-related diseases…

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BACTERIOLOGICAL AND PHYSICOCHEMICAL IMPACT ASSESSMENT OF INDUSTRIAL AND DOMESTIC WASTES ON RIVER SOKOTO

ABSTRACT Bacteriological analysis of the water samples such as heterotrophic counts, coliform counts, Faecal Coliform/Faecal Streptococci (FC/FS) ratio were carried out following standard procedures. Gram-negative…

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ANALGESIC, ANTI-INFLAMMATORY AND OTHER PHARMACOLOGICAL ACTIVITIES OF METHANOL LEAF EXTRACT OF OLAX SUBSCORPIOIDEA OLIV (OLACACEAE) IN LABORATORY ANIMALS

ABSTRACT Synthetic analgesic and anti-inflammatory drugs have major side effects such as constipation, nausea and vomiting, sedation and mental clouding, etc.,which have significantly limited their…

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ANTIBIOGRAM OF UROPATHOGENIC BACTERIA ISOLATED FROM PATIENTS IN SOME HOSPITALS IN BIRNIN KUDU, JIGAWA STATE, NIGER

ABSTRACT Urinary tract infection (UTI) is a common infection of human being and if untreated could lead to serious complications. This study was conducted to…

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AN INTERVENTION STUDY ON MEDICATION ADHERENCE AND CLINICAL OUTCOME AMONG TYPE 2 DIABETIC PATIENTS IN A TERTIARY HEALTH FACILITY IN NIGER STATE NIGERIA

ABSTRACT     Diabetes is one of the leading causes of morbidity and mortality in adults globally. Type 2 diabetes is a disease associated with…

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AMELIORATIVE EFFECT OF RESVERATROL ON LEAD-INDUCED ORGAN TOXICITY IN WISTAR RATS

CHAPTER ONE 1.0  INTRODUCTION 1.1 Background Lead is a heavy, low melting, bluish-gray metal that occurs naturally in the Earth’s crust. However, it is rarely…

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